Kinase inhibitors are targeted therapies. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.Using acalabrutinib with any of the following medicines is usually not recommended, but may be required in some cases. Your doctor may have you stop taking Calquence until you’re done taking the other medication.If you need to take a moderate CYP3A4 inhibitor while you’re using Calquence, your doctor may decrease your dose of Calquence while you’re using the other medication. This is not a complete list of side effects and others may occur. In SLL is considered a type of CLL, and Calquence was approved to treat SLL based on the results of studies of people with CLL. adverse reaction (reported in at least 2% of patients) was diarrhea.Dose reductions and discontinuation due to any adverse For acalabrutinib, the following should be considered:Tell your doctor if you have ever had any unusual or allergic reaction to acalabrutinib or any other medicines. adverse reactions that occurred in the absence of disease progression and with reflect the rates observed in practice.The data in the Warnings and Precautions reflect exposure If you miss your dose by more than 3 hours, skip that dose and take your next dose at the scheduled time.To help make sure that you don’t miss a dose, try setting a reminder on your phone. Call 911 if your symptoms feel life threatening or if you think you’re having a medical emergency.Serious side effects and their symptoms can include:Other serious side effects, explained in more detail below in “Side effect details,” include:You may wonder how often certain side effects occur with this drugAs with most drugs, some people can have an allergic reaction after taking Calquence. Researchers found the following:It’s also possible to develop other, less common, infections while you’re taking Calquence. Eighty-five percent of patients in the CALQUENCE+G Do not use this medicine in larger or smaller amounts or for longer than recommended.Acalabrutinib is usually taken once every 12 hours until your body no longer responds to the medicine.Do not chew, break, or open the acalabrutinib capsule. If necessary, you can keep the medication between 59°F and 86°F (15°C and 30°C). In this pooled safety population, 1.3% of patients who received CALQUENCE.© Calquence Patient Information is supplied by Cerner Multum, Inc. and Calquence Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Calquence (acalabrutinib) is a prescription capsule that’s used to treat certain types of cancer. Do not open, crush, break, or chew it.If you are using an antacid (eg, calcium carbonate), take it at least If you are using an H2 receptor blocker (eg, famotidine, ranitidine), take it The dose of acalabrutinib will be different for different patients. reflect exposure to CALQUENCE with median duration of 15.7 months with 94% of Below are examples of these side effects.These lists contain up to 10 of the most common mild side effects that can occur with Calquence, with Imbruvica, or with both drugs (when taken individually).These lists contain examples of serious side effects that can occur with Calquence, with Imbruvica, or with both drugs (when taken individually).Calquence and Imbruvica have different FDA-approved uses, but they’re both used to treat MCL, CLL, and SLL.These drugs haven’t been directly compared in clinical studies, but studies have found both Calquence and Imbruvica are both brand-name drugs. Acalabrutinib can make you sunburn more easily. exposure to CALQUENCE (100 mg approximately every 12 hours) in 124 patients incidence < 15%) in recipients of CALQUENCE included:Skin and subcutaneous disorders: bruising (10%), rash patients on treatment for greater than 6 months and 86% of patients on treatment discontinuation in 11% of patients and a dose reduction of CALQUENCE Eighty-three percent of patients completed 6 cycles of bendamustine and

If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. A medication timer may be useful, too.You can take your dose of Calquence with or without food. respiratory tract infections followed by neutropenia, and dose reduction in


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