The Government of Canada is not responsible for the accuracy, reliability or currency of the information supplied by external sources. Confidential treatment has been requested with respect to the omitted portions. Novan's cash balance at the end of September was only $55.7 million, which at current spending levels is only estimated to be enough to keep its doors open through the end of 2017. About Molluscum. Confidential treatment has been requested with respect to the omitted portions. Users wishing to rely upon this information should consult directly with the source of the information. [***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Canadian Patents Database / Patent 2865526 Summary Third-party information liability. Confidential treatment has been requested with respect to the omitted portions. The claims pertain to inhibiting a TLR4-mediated immune response via … Confidential treatment has been requested with respect to the omitted portions.For any Royalty-Bearing Products that are sold as combination products in the Oncovirus Field, the Net Sales for such combination products shall be adjusted by multiplying [***] where[***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. [***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. The amounts above are the current amounts if received by December 31 of the current year. Prosecution by Novan; Prosecution of Novan Patents; Filing of Continuations, Divisionals and National Applications by … THIS SECOND AMENDMENT TO NOVAN PATENT AND KNOW-HOW LICENSE AGREEMENT (this “Second Amendment”) is made as of November 2, 2018 (the “Second Amendment Effective Date”) by and between Novan, Inc., a Delaware corporation with a principal place of business at 4105 Hopson Road, Morrisville, North Carolina 27560 (“Novan”), and KNOW Bio, LLC, a North Carolina limited … 1.13 “ Novan Know-How ” means, to the extent Controlled by Novan or any of its Affiliates: (a) all Know-How existing as of the Effective Date that is related to the Novan Patents or the Separately-Licensed Patents; and (b) any New Nitric Oxide Know-How. Molluscum affects approximately six million people in the U.S. annually. KNOW Bio has the right to terminate each such agreement, with notice, for any reason upon ninety days advance written notice to the Company. Novan shall pay to Licensee [***] of the Sublicense Revenues that Novan receives from its sublicensees under all sublicenses of the [***]-Related Patents and [***]-Related Know-How with respect to any Royalty-Bearing Product in the Oncovirus Field granted by Novan. The Government of Canada is not responsible for the accuracy, reliability or currency of the information supplied by external sources. Text of the Claims and Abstract are posted:The present invention generally relates to nitric oxide releasing pharmaceutical compositions and methods of using the same.La présente invention porte d'une façon générale sur des compositions pharmaceutiques libérant de l'oxyde nitrique et sur des procédés d'utilisation de celles-ci.Patent fees are adjusted on the 1st of January every year. [***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Novan to Present at Virtual Life Sciences Investor Forum on June 25 - GlobeNewswire www.globenewswire.com - June 24 at 5:57 PM: Novan (NOVN) granted Canadian patent number 2865526 titled "NITRIC OXIDE RELEASING PHARMACEUTICAL COMPOSITIONS" - PatentGrants - StreetInsider.com www.streetinsider.com - June 23 at 4:52 PM [***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Confidential treatment has been requested with respect to the omitted portions. Some of the information on this Web page has been provided by external sources. Confidential treatment has been requested with respect to the omitted portions. Molluscum contagiosum is a contagious skin infection caused by the molluscipoxvirus. Patent directed to "A method of treating and/or preventing a viral infection in a subject" using Novan's nitric oxide-releasing compounds. Confidential treatment has been requested with respect to the omitted portions. Novan also has the right to terminate each such agreement immediately upon written notice if KNOW Bio, its affiliates or sublicensees challenge the validity of any patent licensed in such agreement. Execution Copy . Confidential treatment has been requested with respect to the omitted portions. Patent Prosecution and Enforcement of Novan Patents Sample Clauses.

[***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Some of the information on this Web page has been provided by external sources. Confidential treatment has been requested with respect to the omitted portions. Content provided by external sources is not subject to official languages, privacy and accessibility requirements.Any discrepancies in the text and image of the Claims and Abstract are due to differing posting times. Cassava Sciences (SAVA) secures a new U.S. patent covering lead candidate sumifilam (PTI-125). [***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. [***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Novan shall make such payment in accordance with Section 2A.4. Past Owners that do not appear in the "Owners on Record" listing will appear in other documentation within the application. Confidential treatment has been requested with respect to the omitted portions. Confidential treatment has been requested with respect to the omitted portions. [***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Novan’s issued U.S. and foreign patents and pending U.S. and foreign patent applications, if issued, relating to SB206 are projected to expire between 2026 and 2034. Novan, Inc. has a license agreement with Sato Pharmaceutical Co., Ltd.; and a strategic alliance with Orion Corporation. Sub-Clauses.

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